-, , ,
A prebiotic is a non-digestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or the activity of one or a limited number of bacteria in the
colon.Prebiotics are like other carbohydrates that reach the cecum, such as nonstars polysaccharides, sugar alcohol, and resistant starch, in being substrates for fermentation. In the
large intestine, prebiotics, in addition to their selective effects on bifidobacteria and lactobacilli, influence manu aspects of bowel function througth fermentation. Short-chain fatty
acidsare a major product of prebiotic breakdown, but as yet, no characteristics pattern of fermentation acids has been identified
Harmful and Beneficial
Bacteroides, b, d, e, f, h, i
Bifidobacterium e, f, h, i
Anaerobic gram + a, b, e
Enterobacteriaceae a, e Lactobacillus e, f, h, i
E.coli a, b, d, f
b: Production of potential
c: Production of toxic H2S Sulfate
d: Intestinal putrefaction
Ps. aeroginosa a
e: Competitive bacterial
f: Stimulation of immune
g: Lower gas distension
h: Aid in food
i: Vitamins synthesis
Predominant colonic microorganisms categorized into potentially harmful or beneficial groups
, [ Puhan, 1999]
DEFINITION FOR PREBIOTICS
A non-digestible food ingredient that beneficially affects the host by selectively stimulating the growth
and/or activity of one or a limited number of bacteria in the colon, and thus improves host health.
Gibson, G.R., Roberfroid, M.B, J. Nutr.(1995) 125, 1401-1412
A dietary prebiotic is a selectively fermented ingredient that results in specific changes, in the
composition and/or activity of the gastrointestinal microbiota, thus conferring benefit(s) upon
PRODUCTION OF OLIGOSACCHARIDES
International Scientific Association for Probiotics & Prebiotics, Nov. 2008, London
SINTES OF GLUCOOLIGOSACCHARIDES BY
SINTES OF GALACTOOLIGOSACCHARIDES BY
TRANSGALACTOSYLATION OF LACTOSE BY
TYPE OF OLIGOSACCHARIDES
-OLIGOSACCHARIDES FROM B-GLUCANS;
-OLIGOSACCHARIDES FROM PECTINS
[-D-Glu]m -D-Fru[-(12)- -DFru]n, m=0-1,n=1-9
+ ( )
-Xyl[l-(14)- -Xyl]n, n=1-8
-D-Glu[-(16)- -D-Glu]n,n=1 4
-D-Glu[-(14)- -D-Glu]n,n=1 - 6
[--D-Glu[-(14)-]n,,n=6 - 12
, (Playne and
We would like to express our gratitude for the support of this work by research grant of NSF Bulgaria RNF 02-02-2009 and FSI 05-248/15.03.2012 of Shumen University.
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